IMMUNOHISTOCHEMICAL EVALUATION OF THYMIC CHANGES IN PRETERM STILLBORN INFANTS

In this period, CD 3, CD 4, Ki 67 markers were studied in order to study the dynamics of T-lymphocytes according to the cellular composition of the morphofunctional active centers in the thymus of stillborn babies . Delays in morphological development in the thyroid gland: the cortex of the thymus is characterized by the fact that it occupies a very small area of the medulla in terms of width, and there are almost no lymphocytes. As the main morphological substrate of these changes, the reticuloepithelial cells of the thymus cortical layer are small in size, the desmasosomes are short and thick, there are many sparse fibrous structures connecting the desmasosomes, and the perivascular areas of the cortical layer show that the hematohistiogenic barrier has become functionally impaired.

Key words: Thymus, immunohistochemistry, involution, immunodeficiency,

necrosis, apoptosis.